《Global Diabetes Mepu》
Vanenge 10% yevakuru vane chirwere cheshuga, uye hafu yavo inoenda isina kuongororwa.
Mumwe muvanhu gumi nevatatu ane abnormal glucose tolerance
Mumwe muvatanhatu vachangozvarwa anobatwa nehyperglycemia panguva yekuzvitakura
Munhu mumwe chete anofa masekonzi masere ega ega kubva kuchirwere cheshuga uye matambudziko acho ...
--------International Diabetes Federatio
Kuwanda kwechirwere cheshuga uye kufa kwakanyanya
Mbudzi 14 izuva reWorld Diabetes Day.Vanofungidzirwa kuti mamiriyoni e463 vanhu vane makore ari pakati pe20 ne79 vanorarama nechirwere cheshuga pasi rose, vazhinji vavo vane Type 2 Diabetes.Izvi zvakaenzana nemunhu mumwe muvakuru gumi nemumwe, maererano neIDF yezvino Diabetes Atlas, chinyorwa chechipfumbamwe cheInternational Diabetes Federation.
Chinotonyanya kutyisa inyaya yekuti chikamu che50.1% chevanhu vakuru pasi rose vane chirwere cheshuga havazivi kuti vanacho.Nekuda kwekushaya rubatsiro rwezveutano, nyika dzine mari shoma ndidzo dzine huwandu hwevarwere vasina kuvhenekwa, pazvikamu makumi matanhatu nezvitanhatu nesere kubva muzana, ukuwo nyika dzine hupfumi hune zvikamu makumi matatu nemasere nemazana matatu kubva muzana zvevarwere vasina kuvhenekwa.
32% yevanhu vane chirwere cheshuga pasi rose vanotambura nechirwere chemwoyo.Kupfuura 80% yekuguma-danho reitsvo chirwere chinokonzerwa nechirwere cheshuga kana hypertension kana zvose zviri zviviri.Matambudziko etsoka nemakumbo ezasi anokanganisa 40 kusvika 60 miriyoni vanhu vane chirwere cheshuga.Vanosvika 11.3% vanofa pasi rose vane chekuita nechirwere cheshuga.Inenge 46.2% yekufa kwakabatana nechirwere cheshuga kwaive pakati pevanhu vari pasi pemakore makumi matanhatu.
Type 2 chirwere cheshuga uye yakakwira body mass index inowedzerawo njodzi yegomarara rakajairika: kusanganisira chiropa, pancreatic, endometrial, colorectal uye mazamu.Parizvino, kurapwa kwechirwere cheshuga kunowanzoitwa nemunhu mumwe nemumwe nemishonga, maekisesaizi uye kudya kwakanaka, uye hakuna mushonga.
Mbanje yekurapa ine 'chinangwa' chechirwere cheshuga
Chidzidzo chitsva chakaburitswa muJournal JAMA Internal Medicine chinoratidza kuti mishonga yembanje inoshanda mukudzikisa zviratidzo mumakonzo ane chirwere cheshuga.Mukuedza, chiitiko chechirwere cheshuga mbeva dzinoshandisa cannabis yakadzikira kubva pa86% kusvika 30%, uye kuzvimba kwepancreas kwakadziviswa uye kunonoka, zvinobudirira kubvisa marwadzo etsinga.Mukuyedza, timu yakawana mhedzisiro yakanaka yembanje yekurapa pachirwere cheshuga:
01
# Regulate metabolism #
Kunonoka kwemasabolism kunoreva kuti muviri haugone kushandisa simba nemazvo, kukanganisa mabasa ekutanga, kusanganisira kutonga kweshuga yeropa, uye zvinotungamira mukufutisa.Mafuta akawandisa mumuviri anoderedza kunzwa kwemasero eropa kune insulin, izvo zvinokanganisa kugona kwavo kutora shuga, inozivikanwawo se insulin resistance.Zvidzidzo zvakaratidza kuti varwere vanoshandisa mbanje yekurapa vane yakaderera insulin kuramba uye nekukurumidza metabolism, iyo inosimudzira "mafuta browning" uye inobatsira chena masero emafuta kushanduka kuita masero ebrown.
metabolized uye inoshandiswa sesimba panguva yekushanda kwemuviri nekudaro kusimudzira zuva rose
kufamba uye metabolism yemasero mumuviri.
02
# Yakaderera insulin kuramba #
Kana masero eropa achiramba insulin, anokundikana kukurudzira kutakurwa kweglucose kuenda kumasero tishu, zvichitungamira mukuvakwa kweglucose.Mbanje yekurapa ine mukana wekuvandudza kugona kwemuviri kutora uye kushandisa insulin nemazvo.Chidzidzo che 2013 chakabudiswa muAmerican Journal of Medicine chakaongorora vanhu vakuru 4,657, varume nevakadzi, uye vakawana kuti varwere vaigara vachishandisa mbanje yezvokurapa vaiva ne16 muzana kuderedza mukutsanya kwe insulin uye 16 muzana kuderedza insulin kuramba.
03
# Deredza kuzvimba kwepancreas #
Kuzvimba kusingaperi kwepancreas masero chiratidzo chekare chechirwere cheshuga 1, kana nhengo dzikazvimba, dzinotadza kuburitsa insulin.Marijuana yekurapa inoshanda mukuderedza kuzvimba, kuderedza kuputika, uye kuenderera mberi kwekuwedzera kunogona kuderedza kusimba kwekuzvimba mupancreas uye kubatsira kunonoka kutanga kwechirwere.
04
# Kurudzira kutenderera kweropa #
Chronic hypertension ndiyo inonyanya kunetsa yerudzi rwekutanga uye Type 2 chirwere cheshuga.Mbanje yezvokurapa inogona kuwedzera tsinga dzeropa, kukurudzira kuyerera kweropa, kudzora zviri nani BP, uye kudzivirira BP.
Muna 2018, mushumo wakaburitswa paConvention on Biological Diversity, inotaura zvakajeka kuti CBD chinhu chakasikwa uye chakachengeteka uye hapana mukana wekushungurudzwa.Kunyangwe pamadhora akakwira se1,500 mg pazuva, hapana mhedzisiro yakaipa.Saka, mbanje yekurapa yakachengeteka here kurapa chirwere cheshuga?Kudyidzana kwezvinodhaka kunoda kutariswa pano.CBD inogona kusangana nemuromo wakaoma uye kushanduka kwechido paunosangana nemamwe madhiragi, asi izvi hazviwanzo.
Ndeipi iyo inokurudzirwa dose yeCBD yechirwere cheshuga?Sangano reUS Food and Drug Administration (FDA) harina kupa mhinduro yakajeka kumubvunzo uyu, nekuti kusimba kwemunhu ega ega, uremu hwemuviri, zera, murume kana mukadzi, uye metabolism zvimwe zvezvinhu zvakawanda zvinofurira.Naizvozvo, chirevo chakajairwa ndechekuti varwere vane chirwere cheshuga vanotanga nekushomeka kwedosi yekuongorora kushandiswa uye kurongeka kwedosi nenguva.Vazhinji vashandisi havangapfuure 25 milligrams yemazuva ese yekudya kweCBD, uye pasi pemamwe mamiriro, iyo yakakwana dosi ye100 mg kusvika 400 mg.
CB2 agonist -caryophyllene BCP inoshanda mumhando ye2 chirwere cheshuga
Vatsvakurudzi veIndia munguva pfupi yapfuura vakabudisa pepa muEuropean Journal of Pharmacology inoratidza kushanda kweCB2 agonist -carbamene BCP pamhando ye2 chirwere cheshuga.Vatsvakurudzi vakawana kuti BCP inogadzirisa zvakananga iyo CB2 receptor pane insulin-inogadzira beta masero ari pancreas, zvichiita kuti insulin isunungurwe uye kudzora kushanda kwakajairika kwepancreas.Panguva imwecheteyo, BCP activation yeCB2 ine mhedzisiro yakanaka pamatambudziko echishuga, akadai senephropathy, retinopathy, cardiomyopathy uye neuropathy.(* CB2 receptors ndiwo makuru ekudzivirira endocannabinoid system;BCP chinhu cheterpene chinowanikwa mumbanje uye mazhinji. girini yakasvibira, muriwo wemashizha.)
# CBD inowedzera kugadzirwa kwe insulin nekuita kuti nherera igamuchire GPR55 #
Vatsvagiri vekuBrazil vanobva kuYunivhesiti yeCalifornia, Marin, vakadzidza nezvehutano hweCBD mumuenzaniso wemhuka wechirwere cheshuga ischemia.Vatsvakurudzi vakakurudzira rudzi rwechipiri rwechirwere cheshuga mumakonzo echirume uye vakawana kuti CBD yaive nemhedzisiro yakanaka pachirwere cheshuga nekuwedzera plasma insulin.
CBD inogona kuderedza shuga yeropa mumakonzo nemamiriro ari kuwedzera nekuda kwekushomeka kweokisijeni.Iyo nzira yekuita inofungidzirwa kuve iyo CBD inogona kuwedzera kugadzirwa kwe insulin nekuita iyo nherera receptor GPR55.Zvisinei, Iko kugona kweCBD kuderedza CB1 chiitiko (seyakashata allosteric regulator) kana kugona kwayo kuita iyo PPAR receptor inogona kukanganisa insulin. release.
Mbanje yekurapa inogona kushandiswa kurapa gomarara, kudzvanya pfari, tsinga dzetsinga, uye matinji, uye kugadzirisa marwadzo.Izvi zvichafambisa kukura, nemusika wepasi rose wembanje yekurapa unotarisirwa kusvika madhora 148.35 bhiriyoni panosvika 2026, maererano nezvazvino chokwadi.《Mishumo uye Data》.
Nguva yekutumira: Zvita-04-2020